Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The expression of tissue factor and tissue factor pathway inhibitor in aortic smooth muscle cells is up-regulated in synthetic compared to contractile phenotype.

Thrombosis and haemostasis - 1 Jun 2002

Ghrib Farida, Brisset Anne-Cécile, Dupouy Dominique, Terrisse Anne-Dominique, Navarro Chantal, Cadroy Yves, Boneu Bernard, Sié Pierre

Abstract excerpt

Tissue factor (TF) and its specific inhibitor TF pathway inhibitor (TFPI) are produced by vascular smooth muscle cells (SMCs) in vitro and are increased in vivo in atherosclerotic compared to normal vessels. Besides local regulation of the hemostatic balance, this may be related to non-hemostatic TF/protease dependent functions such as SMC proliferation, adhesion and migration. The aim of the study was to compare...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aorta
Share to Fibrin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins

Share to Muscle, Smooth, Vascular

Share to Perfusion

Share to Rats, Wistar

Share to Thromboplastin

Share to Thrombosis

Source

Identifiers

PMID: 12083485

Genes

TFPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The expression of tissue factor and tissue factor pathway inhibitor in aortic smooth muscle cells is up-regulated in synthetic compared to contractile phenotype.PMID 12083485Read ↗

NF-κB-Mediated Upregulation of Tissue Factor Contributes to the Procoagulant Phenotype of Smooth Muscle Cells from Abdominal Aorta Aneurysm in Human.Semantic proximity Read ↗

PAF-receptor is preferentially expressed in a distinct synthetic phenotype of smooth muscle cells cloned from human internal thoracic artery: functional implications in cell migration.Semantic proximity Read ↗

Coordinate regulation of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 expression in human vascular smooth muscle cells.Semantic proximity Read ↗

Human-derived vascular smooth muscle cells produce angiotensin II by changing to the synthetic phenotype.Semantic proximity Read ↗

Plasminogen activator expression in rat arterial smooth muscle cells depends on their phenotype and is modulated by cytokines.Semantic proximity Read ↗

Phenotype and function of smooth muscle cells derived from the human normal great saphenous vein in response to hypoxia.Semantic proximity Read ↗

Phenotype gradation of human saphenous vein endothelial cells from cardiovascular disease subjects.Semantic proximity Read ↗

Expression of monocyte chemoattractant protein-1 cDNA in vascular smooth muscle cells: induction of the synthetic phenotype: a possible clue to SMC differentiation in the process of atherogenesis.Semantic proximity Read ↗

Injury induces dedifferentiation of smooth muscle cells and increased matrix-degrading metalloproteinase activity in human saphenous vein.Semantic proximity Read ↗

Synthetic peptides containing a conserved sequence motif of the Id protein family modulate vascular smooth muscle cell phenotype.Semantic proximity Read ↗

Nitric oxide--cyclic GMP pathway regulates vascular smooth muscle cell phenotypic modulation: implications in vascular diseases.Semantic proximity Read ↗

Vascular smooth muscle cells are responsible for a prothrombotic phenotype of spontaneously hypertensive rat arteries.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.