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Article

Role of a molecular variant of rat atrial natriuretic Peptide gene in vascular remodeling.

Annals of clinical and laboratory science - 1 Jan 2007

De Paolis Paola, Nobili Valerio, Lombardi Alessia, Tarasi David, Barbato Daniela, Marchitti Simona, Ganten Ursula, Brunetti Ercole, Volpe Massimo, Rubattu Speranza

Abstract excerpt

Previous studies in a hypertensive animal model of stroke and in humans showed that mutations of the atrial natriuretic peptide (ANP) gene are associated with increased risk of stroke. To elucidate the vascular disease mechanisms that result from structural modifications of the ANP gene, we investigated a coding mutation of the ANP gene in stroke-prone spontaneously hypertensive rats (SHRsp). This mutation leads...

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PMID: 17522368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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