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Article

Role of p38 mitogen-activated protein kinase in thrombus formation.

Journal of receptor and signal transduction research - 1 Jan 2004

Sakurai Kanako, Matsuo Yuji, Sudo Tatsuhiko, Takuwa Yoh, Kimura Sadao, Kasuya Yoshitoshi

Abstract excerpt

The present study was designed to elucidate the role of p38 mitogen-activated protein kinase (p38) in thrombus formation. We used p38alpha heterozygous (p38alpha+/-) mice and used ferric chloride (FeCl3)-induced carotid artery injury as a model of thrombus formation. The time to thrombotic occlusion induced by FeCl3 in p38alpha+/- mice was prolonged compared to that in wild-type (WT) mice. Platelets prepared from...

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Source

Identifiers

PMID: 15648447
DOI: 10.1081/rrs-200040324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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