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Article

Gene expression profiling of MYC-driven tumor signatures in porcine liver stem cells by transcriptome sequencing.

World journal of gastroenterology - 21 Feb 2015

Aravalli Rajagopal N, Talbot Neil C, Steer Clifford J

Abstract excerpt

AIM: To identify the genes induced and regulated by the MYC protein in generating tumors from liver stem cells. METHODS: In this study, we have used an immortal porcine liver stem cell line, PICM-19, to study the role of c-MYC in hepatocarcinogenesis. PICM-19 cells were converted into cancer cells (PICM-19-CSCs) by overexpressing human MYC. To identify MYC-driven differential gene expression, transcriptome...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred NOD

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Share to Proto-Oncogene Proteins c-myc

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Source

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Identifiers

PMID: 25717234
DOI: 10.3748/wjg.v21.i7.2011
PMCID: PMC4326136

Genes

MYC
CDO1
DKK2
ENPEP
GPX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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