Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Central Role of c-Myc during Malignant Conversion in Human Hepatocarcinogenesis

10 Mar 2009

Abstract excerpt

Hepatocarcinogenesis is a multistage process in which precursor lesions progress into early hepatocellular carcinomas (eHCC) by sequential accumulation of multiple genetic and epigenetic alterations. To decode the molecular events during early stages of liver carcinogenesis, we performed gene expression profiling on cirrhotic (regenerative) and dysplastic nodules (DN), as well as eHCC. Although considerable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Chronic Lymphocytic Leukemia Research
Share to Metabolism, Diabetes, and Cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19276364
DOI: 10.1158/0008-5472.can-08-3357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Central Role of c-Myc during Malignant Conversion in Human HepatocarcinogenesisPMID 19276364Read ↗

Identification and validation of functional roles for three MYC-associated genes in hepatocellular carcinomaSemantic proximity Read ↗

c-MYC—Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and DiseaseSemantic proximity Read ↗

Novel Significant Stage-Specific Differentially Expressed Genes in Liver Hepatocellular CarcinomaSemantic proximity Read ↗

Genome-wide expression patterns associated with oncogenesis and sarcomatous transdifferentation of cholangiocarcinomaSemantic proximity Read ↗

Serum MYCN as a predictive biomarker of prognosis and therapeutic response in the prevention of hepatocellular carcinoma recurrenceSemantic proximity Read ↗

The Mutational and Transcriptional Landscapes of Hepatocarcinogenesis in a Rat ModelSemantic proximity Read ↗

Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits.Semantic proximity Read ↗

MYC determines lineage commitment in KRAS-driven primary liver cancer developmentSemantic proximity Read ↗

Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer.Semantic proximity Read ↗

INTS8 is a therapeutic target for intrahepatic cholangiocarcinoma via the integration of bioinformatics analysis and experimental validationSemantic proximity Read ↗

A c-Myc-MicroRNA functional feedback loop affects hepatocarcinogenesisSemantic proximity Read ↗

Identification of NAA40 as a Potential Prognostic Marker for Aggressive Liver Cancer SubtypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.