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Article

Liver-resident CD103+ dendritic cells prime antiviral CD8+ T cells in situ.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2015

Krueger Peter D, Kim Taeg S, Sung Sun-Sang J, Braciale Thomas J, Hahn Young S

Abstract excerpt

The liver maintains a tolerogenic environment to avoid unwarranted activation of its resident immune cells upon continuous exposure to food and bacterially derived Ags. However, in response to hepatotropic viral infection, the liver's ability to switch from a hyporesponsive to a proinflammatory environment is mediated by select sentinels within the parenchyma. To determine the contribution of hepatic dendritic...

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PMID: 25712214
DOI: 10.4049/jimmunol.1402622
PMCID: PMC4369411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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