Article
Mesenteric lymph node CD11b- CD103+ PD-L1High dendritic cells highly induce regulatory T cells.
Immunology - 1 Sept 2017
Shiokawa Aya, Kotaki Ryutaro, Takano Tomohiro, Nakajima-Adachi Haruyo, Hachimura Satoshi
Abstract excerpt
Dendritic cells (DCs) in mesenteric lymph nodes (MLNs) induce Foxp3+ regulatory T cells to regulate immune responses to beneficial or non-harmful agents in the intestine, such as commensal bacteria and foods. Several studies in MLN DCs have revealed that the CD103+ DC subset highly induces regulatory T cells, and another study has reported that MLN DCs from programmed death ligand 1 (PD-L1) -deficient mice could...
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