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Human hepatic stellate cells orchestrate the accumulation and function of CD103 <sup>+</sup> tissue-resident CD8 <sup>+</sup> T-cells in liver fibrosis

2025-12-02

Abstract excerpt

Tissue-resident memory cells (T RM ) contribute to protective and pathogenic responses in the liver, yet precisely how hepatic T RM adapt and integrate cues from the underlying stroma and extracellular matrix (ECM) in chronic liver disease (CLD) has yet to be fully defined. Here we describe a role for activated myofibroblast-like hepatic stellate cells (HSCs) in the accumulation and in situ localisation of CD8...

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Literature Corpus work
6bc069b0-7fab-5aa7-9c0d-749dff8cbc4f
DOI
10.64898/2025.11.28.691193
Open publication

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Human hepatic stellate cells orchestrate the accumulation and function of CD103 <sup>+</sup> tissue-resident CD8 <sup>+</sup> T-cells in liver fibrosisDOI 10.64898/2025.11.28.691193
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