Article
Genetic variations in NADPH-CYP450 oxidoreductase in a Czech Slavic cohort.
Pharmacogenomics - 1 Jan 2015
Tomková Mária, Panda Satya Prakash, Šeda Ondřej, Baxová Alice, Hůlková Martina, Siler Masters Bettie Sue, Martásek Pavel
Abstract excerpt
AIM: Estimating polymorphic allele frequencies of the NADPH-CYP450 oxidoreductase (POR) gene in a Czech Slavic population. METHODS: The POR gene was analyzed in 322 individuals from a control cohort by sequencing and high resolution melting analysis. RESULTS: We identified seven unreported SNP genetic variations, including two SNPs in the 5' flanking region (g.4965C>T and g.4994G>T), one intronic variant...
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