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Article

NADPH P450 oxidoreductase: structure, function, and pathology of diseases.

Pharmacology & therapeutics - 1 May 2013

Pandey Amit V, Flück Christa E

Abstract excerpt

Cytochrome P450 oxidoreductase (POR) is an enzyme that is essential for multiple metabolic processes, chiefly among them are reactions catalyzed by cytochrome P450 proteins for metabolism of steroid hormones, drugs and xenobiotics. Mutations in POR cause a complex set of disorders that often resemble defects in steroid metabolizing enzymes 17α-hydroxylase, 21-hydroxylase and aromatase. Since our initial reports...

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Identifiers

PMID: 23353702
DOI: 10.1016/j.pharmthera.2013.01.010

Genes

POR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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