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Article

Identification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations.

Pharmacogenomics - 1 Apr 2012

Tomková Mária, Marohnic Christopher C, Gurwitz David, Seda Ondřej, Masters Bettie Sue Siler, Martásek Pavel

Abstract excerpt

BACKGROUND: The enzyme NADPH-P450 oxidoreductase (POR) is the main electron donor to all microsomal CYPs. The possible contribution of common POR variants to inter- and intra-individual variability in drug metabolism is of great pharmacogenetic interest. AIM: To search for POR polymorphic alleles and estimate their frequencies in a Jewish population. MATERIALS & METHODS: We analyzed the POR gene in 301 Ashkenazi...

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Source

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Identifiers

PMID: 22462747
DOI: 10.2217/pgs.12.21
PMCID: PMC4270371

Genes

POR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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