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Article

Innate and adaptive genetic pathways in HCV infection.

Tissue antigens - 1 Apr 2015

Buchanan R, Hydes T, Khakoo S I

Abstract excerpt

Infection with hepatitis C virus (HCV) leads to a wide spectrum of clinical manifestations. This heterogeneity is underpinned by the host immune response and the genetic factors that govern it. Polymorphisms affecting both the innate and adaptive immunity determine the outcome of exposure. However the innate immune system appears to play a greater role in determining treatment-associated responses. Overall the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25708172
DOI: 10.1111/tan.12540

Genes

IFNL3

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