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Article

Immunogenetic studies of the hepatitis C virus infection in an era of pan-genotype antiviral therapies - Effective treatment is coming.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2018

Ellwanger Joel Henrique, Kaminski Valéria de Lima, Valverde-Villegas Jacqueline María, Simon Daniel, Lunge Vagner Ricardo, Chies José Artur Bogo

Abstract excerpt

What are the factors that influence human hepatitis C virus (HCV) infection, hepatitis status establishment, and disease progression? Firstly, one has to consider the genetic background of the host and HCV genotypes. The immunogenetic host profile will reflect how each infected individual deals with infection. Secondly, there are environmental factors that drive susceptibility or resistance to certain viral...

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Identifiers

PMID: 28811194
DOI: 10.1016/j.meegid.2017.08.011

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