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Role of Host Genetic Factors in the Outcome of Hepatitis C Virus Infection

5 Aug 2009

Abstract excerpt

The natural history of hepatitis C virus (HCV) infection is determined by a complex interplay between host genetic, immunological and viral factors. This review highlights genes involved in innate and adaptive immune responses associated with different outcomes of HCV infection. For example, an association of HCV clearance with certain HLA alleles has been demonstrated. The mechanisms responsible for these...

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PMID: 21994541
DOI: 10.3390/v1020104

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