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Article

Host genetic variants influencing the clinical course of hepatitis C virus infection.

Journal of medical virology - 1 Feb 2016

Matsuura Kentaro, Tanaka Yasuhito

Abstract excerpt

The clinical course of hepatitis C virus (HCV) infection greatly differs in individuals. Various viral, host, and environmental factors influence the natural history of HCV infection. Recent genome-wide association studies identified several host genetic factors influencing treatment efficacy or clinical course in HCV infection. A landmark discovery was that IFNL3-IFNL4 variants are strongly associated with...

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Share to Carcinoma, Hepatocellular
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Share to IFNL3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Hepatitis C, Chronic

Share to Host-Pathogen Interactions

Share to Liver Cirrhosis

Source

Identifiers

PMID: 26211651
DOI: 10.1002/jmv.24334

Genes

IFNL3
DEPDC5
MERTK
MICA
RNF7
TULP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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