Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A TagSNP in SIRT1 gene confers susceptibility to myocardial infarction in a Chinese Han population.

PloS one - 1 Jan 2015

Cheng Jie, Cho Miook, Cen Jin-ming, Cai Meng-yun, Xu Shun, Ma Ze-wei, Liu Xinguang, Yang Xi-li, Chen Can, Suh Yousin, Xiong Xing-dong

Abstract excerpt

SIRT1 exerts protective effects against endothelial cells dysfunction, inflammation and atherosclerosis, indicating an important role on myocardial infarction (MI) pathogenesis. Nonetheless, the effects of SIRT1 variants on MI risk remain poorly understood. Here we aimed to investigate the influence of SIRT1 polymorphisms on individual susceptibility to MI. Genotyping of three tagSNPs (rs7069102, rs3818292 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged
Share to Alleles
Share to Asian People
Share to China
Share to Gene Frequency
Share to Haplotypes
Share to Myocardial Infarction
Share to Sirtuin 1

Source

Open in PubMed Open full text

Identifiers

PMID: 25706717
DOI: 10.1371/journal.pone.0115339
PMCID: PMC4338141

Genes

SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A TagSNP in SIRT1 gene confers susceptibility to myocardial infarction in a Chinese Han population.PMID 25706717Read ↗

Genetic analysis of the SIRT1 gene promoter in myocardial infarction.Semantic proximity Read ↗

Two tagSNPs rs352493 and rs3760908 within SIRT6 Gene Are Associated with the Severity of Coronary Artery Disease in a Chinese Han Population.Semantic proximity Read ↗

Sequence Variants of SIRT6 Gene Promoter in Myocardial Infarction.Semantic proximity Read ↗

Genetic and Functional Sequence Variants of the SIRT3 Gene Promoter in Myocardial Infarction.Semantic proximity Read ↗

Association of Sirtuin Gene Polymorphisms with Susceptibility to Coronary Artery Disease in a North Chinese Population.Semantic proximity Read ↗

Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus.Semantic proximity Read ↗

SIRT1 gene polymorphisms associated with decreased risk of atherosclerotic coronary artery disease.Semantic proximity Read ↗

Functional genetic variants within the SIRT2 gene promoter in acute myocardial infarction.Semantic proximity Read ↗

Functional genetic variants in the SIRT5 gene promoter in acute myocardial infarction.Semantic proximity Read ↗

Association between the SIRT1 mRNA expression and acute coronary syndrome.Semantic proximity Read ↗

SIRT1 gene polymorphisms affect the protein expression in cardiovascular diseases.Semantic proximity Read ↗

Sirtuin 1 gene polymorphisms are associated with body fat and blood pressure in Japanese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.