Article
Functional genetic variants within the SIRT2 gene promoter in acute myocardial infarction.
PloS one - 1 Jan 2017
Yang Wentao, Gao Feng, Zhang Pei, Pang Shuchao, Cui Yinghua, Liu Lixin, Wei Guanghe, Yan Bo
Abstract excerpt
Coronary artery disease (CAD), including acute myocardial infarction (AMI) is the complication of atherosclerosis. Recently, genome-wide association studies have identified a large number of CAD-related genetic variants. However, only 10% of CAD cases could be explained. Low frequent and rare genetic variants have been recently proposed to be main causes for CAD. SIRT2 is a member of sirtuin family,...
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