Article
Sequence Variants of SIRT6 Gene Promoter in Myocardial Infarction.
Genetic testing and molecular biomarkers - 1 Apr 2016
Wang Lekun, Ma Ling, Pang Shuchao, Huang Jian, Yan Bo
Abstract excerpt
AIMS: Coronary artery disease (CAD), including myocardial infarction (MI), is a common complex disease caused by atherosclerosis. Although more than 50 genetic variants have been associated with CAD, these loci collectively account for only 10% of CAD cases. Genetic variants of low and rare frequencies have been proposed as the main causes of CAD. SIRT6, one of the highly conserved NAD-dependent class III...
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