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Article

Two tagSNPs rs352493 and rs3760908 within SIRT6 Gene Are Associated with the Severity of Coronary Artery Disease in a Chinese Han Population.

Disease markers - 1 Jan 2016

Tang Sai-sai, Xu Shun, Cheng Jie, Cai Meng-yun, Chen Lin, Liang Li-li, Yang Xi-li, Chen Can, Liu Xin-guang, Xiong Xing-dong

Abstract excerpt

SIRT6 has been demonstrated to exert protective effects on endothelial cells and is closely associated with lipid metabolism, glucose metabolism, and obesity, indicating an important role in the pathogenesis and progression of coronary artery disease (CAD). Nonetheless, the biological significance of SIRT6 variants on CAD is far to be elucidated. Here we aimed to investigate the influence of SIRT6 polymorphisms...

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Source

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Identifiers

PMID: 27118880
DOI: 10.1155/2016/1628041
PMCID: PMC4826929

Genes

CAD
SIRT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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