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Article

Genetic and Functional Sequence Variants of the SIRT3 Gene Promoter in Myocardial Infarction.

PloS one - 1 Jan 2016

Yin Xiaoyun, Pang Shuchao, Huang Jian, Cui Yinghua, Yan Bo

Abstract excerpt

Coronary artery disease (CAD), including myocardial infarction (MI), is a common complex disease that is caused by atherosclerosis. Although a large number of genetic variants have been associated with CAD, only 10% of CAD cases could be explained. It has been proposed that low frequent and rare genetic variants may be main causes for CAD. SIRT3, a mitochondrial deacetylase, plays important roles in mitochondrial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27078640
DOI: 10.1371/journal.pone.0153815
PMCID: PMC4831762

Genes

SIRT3
CAD

Provenance

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