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Article

Estrogen receptor α in osteocytes regulates trabecular bone formation in female mice.

Bone - 1 Mar 2014

Kondoh Shino, Inoue Kazuki, Igarashi Katsuhide, Sugizaki Hiroe, Shirode-Fukuda Yuko, Inoue Erina, Yu Taiyong, Takeuchi Jun K, Kanno Jun, Bonewald Lynda F, Imai Yuuki

Abstract excerpt

Estrogens are well known steroid hormones necessary to maintain bone health. In addition, mechanical loading, in which estrogen signaling may intersect with the Wnt/β-catenin pathway, is essential for bone maintenance. As osteocytes are known as the major mechanosensory cells embedded in mineralized bone matrix, osteocyte ERα deletion mice (ERα(ΔOcy/ΔOcy)) were generated by mating ERα floxed mice with Dmp1-Cre...

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Identifiers

PMID: 24333171
DOI: 10.1016/j.bone.2013.12.005
PMCID: PMC3944732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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