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Article

T helper 9 cells induced by plasmacytoid dendritic cells regulate interleukin-17 in multiple sclerosis.

Clinical science (London, England : 1979) - 1 Aug 2015

Ruocco Gabriella, Rossi Silvia, Motta Caterina, Macchiarulo Giulia, Barbieri Francesca, De Bardi Marco, Borsellino Giovanna, Finardi Annamaria, Grasso Maria Grazia, Ruggieri Serena, Gasperini Claudio, Furlan Roberto, Centonze Diego, Battistini Luca, Volpe Elisabetta

Abstract excerpt

Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) characterized by persistent inflammation orchestrated by cluster of differentiation (CD) 4 T helper (Th) cells. In particular, Th1 and Th17 cells amplify, whereas T regulatory (Treg) cells moderate inflammation. The role of other Th subsets in MS is not clear. In the present study, we investigated the generation of different Th...

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Identifiers

PMID: 25700150
DOI: 10.1042/CS20140608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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