Article
Circulating dendritic cells of multiple sclerosis patients are proinflammatory and their frequency is correlated with MS-associated genetic risk factors.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Apr 2014
Thewissen Kristof, Nuyts Amber H, Deckx Nathalie, Van Wijmeersch Bart, Nagels Guy, D'hooghe Marie, Willekens Barbara, Cras Patrick, Eijnde Bert O, Goossens Herman, Van Tendeloo Viggo F I, Stinissen Piet, Berneman Zwi N, Hellings Niels, Cools Nathalie
Abstract excerpt
BACKGROUND: The role of the adaptive immune system and more specifically T cells in the pathogenesis of multiple sclerosis (MS) has been studied extensively. Emerging evidence suggests that dendritic cells (DCs), which are innate immune cells, also contribute to MS. OBJECTIVES: This study aimed t...
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