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Article

Interferon-β regulates dendritic cell activation and migration in experimental autoimmune encephalomyelitis.

Immunology - 1 Nov 2017

Pennell Leesa M, Fish Eleanor N

Abstract excerpt

CD11c+ dendritic cells (DCs) exert a critical role as antigen-presenting cells in regulating pathogenic T cells in multiple sclerosis (MS). To determine whether the therapeutic benefit of interferon-β (IFN-β) treatment for MS is in part influenced by IFN regulation of DC function, we examined the immunophenotype of DCs derived from IFN-β+/+ and IFN-β-/- mice using a myelin oligodendrocyte glycoprotein (MOG)...

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Topics

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Share to Adoptive Transfer
Share to CD11c Antigen
Share to Cell Plasticity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Encephalomyelitis, Autoimmune, Experimental

Share to Interferon-beta

Share to Myelin-Oligodendrocyte Glycoprotein

Share to Receptors, CCR7

Share to STAT1 Transcription Factor

Source

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Identifiers

PMID: 28646573
DOI: 10.1111/imm.12781
PMCID: PMC5629448

Genes

MOG
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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