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Article

Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis.

Brain : a journal of neurology - 1 Dec 2009

Brucklacher-Waldert Verena, Stuerner Klarissa, Kolster Manuela, Wolthausen Julia, Tolosa Eva

Abstract excerpt

Multiple sclerosis is a T cell-mediated demyelinating disease of the central nervous system. Interleukin-17-producing T helper cells, named Th17 cells, represent a novel CD4+ T cell effector subset involved in the response against extracellular pathogens. In addition, Th17 cells are pathogenic in several animal models of autoimmune disease, including the animal model for multiple sclerosis, but their function in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19933767
DOI: 10.1093/brain/awp289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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