A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer.

doi:10.1158/2159-8290.CD-14-1057

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Article

A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer.

Cancer discovery - 1 Apr 2015

Stegeman Shane, Amankwah Ernest, Klein Kerenaftali, O'Mara Tracy A, Kim Donghwa, Lin Hui-Yi, Permuth-Wey Jennifer, Sellers Thomas A, Srinivasan Srilakshmi, Eeles Rosalind, Easton Doug, Kote-Jarai Zsofia, Amin Al Olama Ali, Benlloch Sara, Muir Kenneth, Giles Graham G, Wiklund Fredrik, Gronberg Henrik, Haiman Christopher A, Schleutker Johanna, Nordestgaard Børge G, Travis Ruth C, Neal David, Pharoah Paul, Khaw Kay-Tee, Stanford Janet L, Blot William J, Thibodeau Stephen, Maier Christiane, Kibel Adam S, Cybulski Cezary, Cannon-Albright Lisa, Brenner Hermann, Kaneva Radka, Teixeira Manuel R, Spurdle Amanda B, Clements Judith A, Park Jong Y, Batra Jyotsna

Abstract excerpt

UNLABELLED: Prostate cancer is the second most common malignancy among men worldwide. Genome-wide association studies have identified 100 risk variants for prostate cancer, which can explain approximately 33% of the familial risk of the disease. We hypothesized that a comprehensive analysis of genetic variations found within the 3' untranslated region of genes predicted to affect miRNA binding (miRSNP) can...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25691096
DOI: 10.1158/2159-8290.CD-14-1057
PMCID: PMC4390388

Genes

KLK3
VAMP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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