Article
Mapping genetic variability in mature miRNAs and miRNA binding sites in prostate cancer.
Journal of human genetics - 1 Nov 2021
Lee Bongyong, Li Jian-Liang, Marchica John, Mercola Mark, Patel Vipul, Perera Ranjan J
Abstract excerpt
MicroRNAs (miRNAs) regulate diverse cancer hallmarks through sequence-specific regulation of gene expression, so genetic variability in their seed sequences or target sites could be responsible for cancer initiation or progression. While several efforts have been made to predict the locations of single nucleotide variants (SNVs) at miRNA target sites and associate them with cancer risk and susceptibility, there...
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