Article
Mechanism of siRNA production from repetitive DNA.
Genes & development - 1 Mar 2015
Yang Qiuying, Ye Qiaohong Anne, Liu Yi
Abstract excerpt
RNAi is a conserved genome defense mechanism in eukaryotes that protects against deleterious effects of transposons and viral invasion. Repetitive DNA loci are a major source for the production of eukaryotic small RNAs, but how these small RNAs are produced is not clear. Quelling in Neurospora is one of the first known RNAi-related phenomena and is triggered by the presence of multiple copies of transgenes. Here...
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