Article
Premeiotic instability of repeated sequences in Neurospora crassa.
Annual review of genetics - 1 Jan 1990
Selker E U
Abstract excerpt
Maintenance of a steamlined genome is probably important to a free-living fungus. The period between fertilization and karyogamy in the life cycle of Neurospora and related fungi provides an ideal time for "genome-cleaning". Premeiotic intrachromosomal recombination deletes tandem repeats at high frequency in both homothallic and heterothallic filamentous ascomycetes. This eliminates excess copies of tandemly...
Topics
- DNA, Fungal
- Genes, Fungal
- Meiosis
- Mutation
- Neurospora crassa
- Recombination, Genetic
- Repetitive Sequences, Nucleic Acid
- Transformation, Genetic
