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Article

Two-step recruitment of RNA-directed DNA methylation to tandem repeats.

PLoS biology - 1 Nov 2006

Chan Simon W-L, Zhang Xiaoyu, Bernatavichute Yana V, Jacobsen Steven E

Abstract excerpt

Tandem repeat sequences are frequently associated with gene silencing phenomena. The Arabidopsis thaliana FWA gene contains two tandem repeats and is an efficient target for RNA-directed de novo DNA methylation when it is transformed into plants. We showed that the FWA tandem repeats are necessary and sufficient for de novo DNA methylation and that repeated character rather than intrinsic sequence is likely...

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Source

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Identifiers

PMID: 17105345
DOI: 10.1371/journal.pbio.0040363
PMCID: PMC1618421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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