Article
Distinct and concurrent pathways of Pol II- and Pol IV-dependent siRNA biogenesis at a repetitive trans-silencer locus in Arabidopsis thaliana.
The Plant journal : for cell and molecular biology - 1 Jul 2014
Sasaki Taku, Lee Tzuu-fen, Liao Wen-Wei, Naumann Ulf, Liao Jo-Ling, Eun Changho, Huang Ya-Yi, Fu Jason L, Chen Pao-Yang, Meyers Blake C, Matzke Antonius J M, Matzke Marjori
Abstract excerpt
Short interfering RNAs (siRNAs) homologous to transcriptional regulatory regions can induce RNA-directed DNA methylation (RdDM) and transcriptional gene silencing (TGS) of target genes. In our system, siRNAs are produced by transcribing an inverted DNA repeat (IR) of enhancer sequences, yielding a hairpin RNA that is processed by several Dicer activities into siRNAs of 21-24 nt. Primarily 24-nt siRNAs trigger...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
