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Genetic variants in the inositol phosphate metabolism pathway and risk of different types of cancer.

Scientific reports - 16 Feb 2015

Tan Juan, Yu Chen-Yang, Wang Zhen-Hua, Chen Hao-Yan, Guan Jian, Chen Ying-Xuan, Fang Jing-Yuan

Abstract excerpt

Members of the inositol phosphate metabolism pathway regulate cell proliferation, migration and phosphatidylinositol-3-kinase (PI3K)/Akt signaling, and are frequently dysregulated in cancer. Whether germline genetic variants in inositol phosphate metabolism pathway are associated with cancer risk remains to be clarified. We examined the association between inositol phosphate metabolism pathway genes and risk of...

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PMID: 25683757
DOI: 10.1038/srep08473
PMCID: PMC4329558

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Source receipt: pubmed, retrieved 7 Sept 2026.

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