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Article

TGF‐βRII / EP300 /SMAD4 cascade signaling pathway promotes invasion and glycolysis in oral squamous cell carcinoma

14 Mar 2023

Abstract excerpt

INTRODUCTION: EP300 is considered to be a cancer suppressor gene that plays a role in tumor development, but some studies have reported that it is not an oral squamous cell carcinoma suppressor gene, because there was neither epigenetic inactivation of the gene nor a mutation resulting in functional impairment. However, there is no relevant study on whether EP300 is the exact carcinogenic effect and its...

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PMID: 36916236
DOI: 10.1111/jop.13424

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