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Article

Polymorphisms in RAS/RAF/MEK/ERK Pathway Are Associated with Gastric Cancer

28 Dec 2018

Abstract excerpt

The RAS/RAF/MEK/ERK pathway regulates certain cellular functions, including cell proliferation, differentiation, survival, and apoptosis. Dysregulation of this pathway leads to the occurrence and progression of cancers mainly by somatic mutations. This study aimed to assess if polymorphisms of the RAS/RAF/MEK/ERK pathway are associated with gastric cancer. A case-control study of 242 gastric cancer patients and...

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PMID: 30597917
DOI: 10.3390/genes10010020

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