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Article

Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival.

Oncotarget - 28 Feb 2015

Kim Sangkyu, Welsh David A, Myers Leann, Cherry Katie E, Wyckoff Jennifer, Jazwinski S Michal

Abstract excerpt

We have completed a genome-wide linkage scan for healthy aging using data collected from a family study, followed by fine-mapping by association in a separate population, the first such attempt reported. The family cohort consisted of parents of age 90 or above and their children ranging in age from 50 to 80. As a quantitative measure of healthy aging, we used a frailty index, called FI34, based on 34 health and...

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Identifiers

PMID: 25682868
DOI: 10.18632/oncotarget.2877
PMCID: PMC4414140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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