Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in healthy oldest-old.

PloS one - 14 Aug 2009

Halaschek-Wiener Julius, Amirabbasi-Beik Mahsa, Monfared Nasim, Pieczyk Markus, Sailer Christian, Kollar Anita, Thomas Ruth, Agalaridis Georgios, Yamada So, Oliveira Lisa, Collins Jennifer A, Meneilly Graydon, Marra Marco A, Madden Kenneth M, Le Nhu D, Connors Joseph M, Brooks-Wilson Angela R

Abstract excerpt

Individuals who live to 85 and beyond without developing major age-related diseases may achieve this, in part, by lacking disease susceptibility factors, or by possessing resistance factors that enhance their ability to avoid disease and prolong lifespan. Healthy aging is a complex phenotype like...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to SIRT1 gene

Share to UCP2 gene

Share to UCP3 gene

Share to Genetic Variation

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 19680556
DOI: 10.1371/journal.pone.0006641
PMCID: PMC2722017

Genes

APOB
BECN1
CRYAB
DLL1
HSPB2
ING1
LMNA
NOTCH1
PPARG
SCD
SIRT1
SIRT3
TRDMT1
UCP2
UCP3
ZMPSTE24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19680556-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in healthy oldest-old.PMID 19680556Read ↗

Whole-Genome Sequencing of a Healthy Aging Cohort.Semantic proximity Read ↗

Genetic variation and human aging: progress and prospects.Semantic proximity Read ↗

Genetics of healthy aging and longevity.Semantic proximity Read ↗

Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old.Semantic proximity Read ↗

Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participantsSemantic proximity Read ↗

The role of genetic variants in human longevity.Semantic proximity Read ↗

Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study.Semantic proximity Read ↗

Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges.Semantic proximity Read ↗

Study designs to enhance identification of genetic factors in healthy aging.Semantic proximity Read ↗

The Medical Genome Reference Bank: a whole-genome data resource of 4,000 healthy elderly individuals. Rationale and cohort designSemantic proximity Read ↗

LongevityMap: a database of human genetic variants associated with longevity.Semantic proximity Read ↗

The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.