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Article

Genetic variation in healthy oldest-old.

PloS one - 14 Aug 2009

Halaschek-Wiener Julius, Amirabbasi-Beik Mahsa, Monfared Nasim, Pieczyk Markus, Sailer Christian, Kollar Anita, Thomas Ruth, Agalaridis Georgios, Yamada So, Oliveira Lisa, Collins Jennifer A, Meneilly Graydon, Marra Marco A, Madden Kenneth M, Le Nhu D, Connors Joseph M, Brooks-Wilson Angela R

Abstract excerpt

Individuals who live to 85 and beyond without developing major age-related diseases may achieve this, in part, by lacking disease susceptibility factors, or by possessing resistance factors that enhance their ability to avoid disease and prolong lifespan. Healthy aging is a complex phenotype likely to be affected by both genetic and environmental factors. We sequenced 24 candidate healthy aging genes in DNA...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19680556
DOI: 10.1371/journal.pone.0006641
PMCID: PMC2722017

Genes

APOB
BECN1
CDKN2A
CRYAB
DLL1
DNMT3A
DNMT3B
HSPB2
IGF1R
ING1
KL
LMNA
NOTCH1
PPARG
PPARGC1A
SCD
SIRT1
SIRT3
TP53
TRDMT1
UCP2
UCP3
ZMPSTE24

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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