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Article

Control of ethanol sensitivity of the glycine receptor α3 subunit by transmembrane 2, the intracellular splice cassette and C-terminal domains.

The Journal of pharmacology and experimental therapeutics - 1 Apr 2015

Sánchez Andrea, Yévenes Gonzalo E, San Martin Loreto, Burgos Carlos F, Moraga-Cid Gustavo, Harvey Robert J, Aguayo Luis G

Abstract excerpt

Previous studies have shown that the effect of ethanol onglycine receptors (GlyRs) containing the a1 subunit is affected by interaction with heterotrimeric G proteins (Gβγ). GlyRs containing the α3 subunit are involved in inflammatory pain sensitization and rhythmic breathing and have received much recent attention. For example, it is unknown whether ethanol affects the function of this important GlyR subtype....

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Identifiers

PMID: 25589412
DOI: 10.1124/jpet.114.221143
PMCID: PMC4366752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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