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Article

Alzheimer's disease is associated with low density of the long CR1 isoform.

Neurobiology of aging - 1 Apr 2015

Mahmoudi Rachid, Kisserli Aymric, Novella Jean-Luc, Donvito Béatrice, Dramé Moustapha, Réveil Brigitte, Duret Valérie, Jolly Damien, Pham Bach-Nga, Cohen Jacques H

Abstract excerpt

The long complement receptor type 1 (CR1) isoform, CR1*2 (S), has been identified as being associated with Alzheimer's disease (AD) risk. We aimed to analyze the phenotypic structural and expression aspects (length and density) of CR1 in erythrocytes of 135 Caucasian subjects (100 AD and 35 controls). CR1 length polymorphism was assessed at protein and gene levels using Western blot and high-resolution melting,...

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PMID: 25666996
DOI: 10.1016/j.neurobiolaging.2015.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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