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Article

Complement receptor 1 (CR1) and Alzheimer's disease.

Immunobiology - 1 Feb 2012

Crehan Helen, Holton Patrick, Wray Selina, Pocock Jennifer, Guerreiro Rita, Hardy John

Abstract excerpt

Alzheimer's disease (AD) is the most common neurodegenerative disease and it poses an ever-increasing burden to an aging population. Several loci responsible for the rare, autosomal dominant form of AD have been identified (APP, PS1 and PS2), and these have facilitated the development of the amyloid cascade hypothesis of AD aetiology. The late onset form of the disease (LOAD) is poorly defined genetically, and up...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21840620
DOI: 10.1016/j.imbio.2011.07.017

Genes

APOE
APP
CLU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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