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Article

LINGO family receptors are differentially expressed in the mouse brain and form native multimeric complexes

30 Aug 2020

Abstract excerpt

Leucine-rich repeat and immunoglobin-domain containing (LRRIG) proteins that are commonly involved in protein-protein interactions play important roles in nervous system development and maintenance. LINGO-1, one of this family members, is characterized as a negative regulator of neuronal survival, axonal regeneration, and oligodendrocyte precursor cell (OPC) differentiation into mature myelinating...

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PMID: 32862444
DOI: 10.1096/fj.202000826r

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