Article
Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery.
Gut - 1 Apr 2016
Reinert Thomas, Schøler Lone V, Thomsen Rune, Tobiasen Heidi, Vang Søren, Nordentoft Iver, Lamy Philippe, Kannerup Anne-Sofie, Mortensen Frank V, Stribolt Katrine, Hamilton-Dutoit Stephen, Nielsen Hans J, Laurberg Søren, Pallisgaard Niels, Pedersen Jakob S, Ørntoft Torben F, Andersen Claus L
Abstract excerpt
OBJECTIVE: To develop an affordable and robust pipeline for selection of patient-specific somatic structural variants (SSVs) being informative about radicality of the primary resection, response to adjuvant therapy, incipient recurrence and response to treatment performed in relation to diagnosis of recurrence. DESIGN: We have established efficient procedures for identification of SSVs by next-generation...
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