Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies.

doi:10.1002/ijc.33312

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Article

Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies.

International journal of cancer - 15 Feb 2021

Tie Jeanne, Cohen Joshua D, Lo Serigne N, Wang Yuxuan, Li Lu, Christie Michael, Lee Margaret, Wong Rachel, Kosmider Suzanne, Skinner Iain, Wong Hui Li, Lee Belinda, Burge Matthew E, Yip Desmond, Karapetis Christos S, Price Timothy J, Tebbutt Niall C, Haydon Andrew M, Ptak Janine, Schaeffer Mary J, Silliman Natalie, Dobbyn Lisa, Popoli Maria, Tomasetti Cristian, Papadopoulos Nickolas, Kinzler Kenneth W, Vogelstein Bert, Gibbs Peter

Abstract excerpt

Studies in multiple solid tumor types have demonstrated the prognostic significance of ctDNA analysis after curative intent surgery. A combined analysis of data across completed studies could further our understanding of circulating tumor DNA (ctDNA) as a prognostic marker and inform future trial design. We combined individual patient data from three independent cohort studies of nonmetastatic colorectal cancer...

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Identifiers

PMID: 32984952
DOI: 10.1002/ijc.33312
PMCID: PMC8818130

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Source receipt: pubmed, retrieved 7 Sept 2026.

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