Article
Dynamic changes in longitudinal circulating tumour DNA profile during metastatic colorectal cancer treatment.
British journal of cancer - 1 Sept 2022
Kim Sheehyun, Lim Yoojoo, Kang Jun-Kyu, Kim Hwang-Phill, Roh Hanseong, Kim Su Yeon, Lee Dongin, Bang Duhee, Jeong Seung-Yong, Park Kyu Joo, Han Sae-Won, Kim Tae-You
Abstract excerpt
BACKGROUND: Circulating tumour DNA (ctDNA) has been spotlighted as an attractive biomarker because of its easy accessibility and real-time representation of tumour genetic profile. However, the clinical utility of longitudinal ctDNA monitoring has not been clearly defined. METHODS: Serial blood samples were obtained from metastatic colorectal cancer patients undergoing first-line chemotherapy. ctDNA was sequenced...
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