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Article

Application of Circulating Tumor DNA as a Non-Invasive Tool for Monitoring the Progression of Colorectal Cancer.

PloS one - 1 Jan 2016

Zhou Jiaolin, Chang Lianpeng, Guan Yanfang, Yang Ling, Xia Xuefeng, Cui Liqiang, Yi Xin, Lin Guole

Abstract excerpt

BACKGROUND: Liquid biopsy has been proposed to be a promising noninvasive tool to obtain information on tumor progression. Through a clinical observation of a case series of 6 consecutive patients, we aim to determine the value of circulating tumor DNA (ctDNA) for monitoring the tumor burden during the treatment of colorectal cancer (CRC). MATERIALS AND METHODS: We used capture sequencing of 545 genes to identify...

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Identifiers

PMID: 27459628
DOI: 10.1371/journal.pone.0159708
PMCID: PMC4961398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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