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Article

Locally performed postoperative circulating tumour DNA testing performed during routine clinical care to predict recurrence of colorectal cancer.

ANZ journal of surgery - 1 Oct 2023

Cohen Ryan, Beasley Aaron, McCoy Melanie, Platell Cameron, Meehan Katie, Gray Elin, Fuller Kathy

Abstract excerpt

BACKGROUND: Identifying patients at high risk for colorectal cancer recurrence is essential for improving prognosis. In the postoperative period, circulating tumour DNA (ctDNA) has been demonstrated as a significant prognostic indicator of recurrence. These results have been obtained under the strict rigours of clinical trials, but not validated in a real-world setting using in-house testing. We report the...

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PMID: 36921099
DOI: 10.1111/ans.18385

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