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Article

Deficiency in the Formation of 20-Hydroxyeicosatetraenoic Acid Enhances Renal Ischemia-Reperfusion Injury.

Journal of the American Society of Nephrology : JASN - 1 Oct 2015

Muroya Yoshikazu, Fan Fan, Regner Kevin R, Falck John R, Garrett Michael R, Juncos Luis A, Roman Richard J

Abstract excerpt

Ischemia-reperfusion (IR) injury is the most common cause of AKI. The susceptibility to develop AKI varies widely among patients. However, little is known about the genes involved. 20-Hydroxyeicosatetraenoic acid (20-HETE) has an important role in the regulation of renal tubular and vascular function and has been implicated in IR injury. In this study, we examined whether a deficiency in the renal formation of...

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Identifiers

PMID: 25644108
DOI: 10.1681/ASN.2014090868
PMCID: PMC4587700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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