ID4 gene polymorphism and osteoporosis in Thai menopausal women.

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Article

ID4 gene polymorphism and osteoporosis in Thai menopausal women.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Oct 2014

Chupeerach Chaowanee, Kulanuwat Sirikul, Chuenta Wanida, Wannaiampikul Sivaporn, Schuh Vanessa Anne, Preutthipan Sangchai, Tungtrongchitr Rungsunn

Abstract excerpt

BACKGROUND: The inhibitor of DNA binding 4 (ID4) protein regulates osteogenic and adipogenic cell fate and lack of lD4 gene expression decreased osteoblast differentiation. Variant in the ID4 gene polymorphism has not been reported with osteoporosis. OBJECTIVE: To identify whether ID4 can be a marker gene for osteoporosis in Thai menopausal women. MATERIAL AND METHOD: The 3 'UTR of lD4 (rs3798339) single...

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PMID: 25632614

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