Article
A common LRP4 haplotype is associated with bone mineral density and hip geometry in men-data from the Odense Androgen Study (OAS).
Bone - 1 Apr 2013
Boudin Eveline, Steenackers Ellen, de Freitas Fenna, Nielsen Torben Leo, Andersen Marianne, Brixen Kim, Van Hul Wim, Piters Elke
Abstract excerpt
Osteoporosis is a common disease characterized by an increased susceptibility to fracture. It is a complex disorder resulting from the interaction of several polymorphisms in different genes and environmental factors. Since we recently reported a role for low density lipoprotein-related protein (LRP)-4 in monogenic disorders with bone overgrowth, we now wanted to evaluate whether genetic variation in the LRP4...
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