Article
Association of LRP5 genotypes with osteoporosis in Tunisian post-menopausal women.
BMC musculoskeletal disorders - 30 Apr 2014
Sassi Rim, Sahli Hela, Souissi Chiraz, El Mahmoudi Hejer, Zouari Bechir, Ben Ammar ElGaaied Amel, Sellami Slaheddine, Ferrari Serge Livio
Abstract excerpt
BACKGROUND: Osteoporosis is a highly heritable trait. Among the genes associated with bone mineral density (BMD), the low-density lipoprotein receptor-related protein 5 gene (LRP5) has been consistently identified in Caucasians. However LRP5 contribution to osteoporosis in populations of other ethnicities remains poorly known. METHODS: To determine whether LRP5 polymorphisms Ala1330Val and Val667Met are...
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