Article
Wnt16 attenuates TGFβ-induced chondrogenic transformation in vascular smooth muscle.
Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2015
Beazley Kelly E, Nurminsky Dmitry, Lima Florence, Gandhi Chintan, Nurminskaya Maria V
Abstract excerpt
OBJECTIVE: Phenotypic plasticity of vascular smooth muscle cells (VSMCs) contributes to cardiovascular disease. Chondrocyte-like transformation of VSMCs associates with vascular calcification and underlies the formation of aortic cartilaginous metaplasia induced in mice by genetic loss of matrix...
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